Ingestible capsule has potential to improve diagnostics for GI disease

Current diagnostic methods for small intestinal bacterial overgrowth (SIBO) can be invasive, costly, or unreliable. A novel ingestible capsule shows promise as a preferred tool for SIBO diagnosis.

We interviewed 100 gastroenterologists and experts to understand how clinicians diagnose SIBO, their concerns regarding methods and treatment, and their preference for a potential novel diagnostic test.

What did we find?

  • Most gastroenterologists are dissatisfied with the currently available options to diagnose SIBO.
  • The most common diagnostic workup for SIBO is breath testing and empiric antibiotic therapy. However, there are concerns about the accuracy of breath testing results.
  • Few providers perform "gold standard" small bowel aspiration and culture.
The ingestible capsule is viewed favorably and has the potential to replace both endoscopic aspiration and hydrogen breath testing as the preferred diagnostic tool for suspected SIBO cases.
This research was presented at the 2020 American College of Gastroenterology (ACG) annual meeting. Download the poster