Important ACOG Recommendation Updates

In March 2017, the American College of Obstetricians and Gynecologists (ACOG) issued two new Committee Opinions regarding carrier testing for patients who are pregnant or considering pregnancy.

Carrier testing for SMA is now recommended for all patients, regardless of ethnicity or family history.

“Screening for spinal muscular atrophy should be offered to all women who are considering pregnancy or are currently pregnant.”

ACOG Committee Opinion No. 691

Carrier Screening for Genetic Conditions

March 2017

If your practice is not offering screening for spinal muscular atrophy to all patients, your protocol likely needs an update. Progenity includes SMA testing with all Preparent™ Carrier Screen panels.

SMA is an autosomal recessive genetic disorder that causes progressive muscle wasting and weakness. It is the most common genetic cause of infant death, and the carrier frequency is about 1 in 50 in the general population. When both parents are carriers, there is a 1 in 4 chance the child will be affected.

Practices should establish standard clinical protocols, and consider expanded carrier testing panels.

“Ethnic-specific, panethnic, and expanded carrier screening are acceptable strategies for prepregnancy and prenatal carrier screening. Each... practice should establish a standard approach that is consistently offered to and discussed with each patient, ideally before pregnancy.”

ACOG Committee Opinion No. 690

Carrier Screening in the Age of Genomic Medicine

March 2017

What does this mean for you? Consider evaluating your clinical workflow to ensure that all patients are routinely offered carrier testing. Progenity provides a variety of tools to make it easy to establish a clinical protocol, including quick reference cards for pre-test counseling, patient education resources, and informed consent forms.

Consistent with our commitment to education and service, we are working to make healthcare providers aware of these changes and help assess the impact they may have on clinical practices. Your local Progenity representative can provide more information about the new ACOG guidelines, and help you ensure that your carrier testing protocol is up to date.